Поддерживающее исследование
Red blood cell membrane and adipose tissue lipids were analysed as an indication of short-term and long-term dietary fatty acid in a family with autosomal dominant Stargatdt’s macular dystrophy. When adipose lipids were analysed, there was a significant inverse relationship between phenotypic severity and the level of eicosapentaenoic acid. When red blood cell lipids were analysed, there were significant inverse relationships between phenotypic severity and levels of eicosapentaenoic and docosahexanoic fatty acids.
The retinal outer nuclear layer is found reduced in patients with macular dystrophies. When mice models with Stargart’s disease were treated with Omega 3 the thickness of the retinal outer nuclear layer increased a considerable amount.
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