Glaucoma

It is estimated that 50% of people with glaucoma are unaware that they have the disease, and those who have it can sometimes only slow down its progression. Glaucoma causes damage to your eye’s optic nerve, which gets worse over time. It is most commonly caused by fluid building up at the front of the eye, resulting in increased eye pressure. Glaucoma treatment depends on the type of glaucoma you have, but the main focus is on lowering the eye pressure. While it progresses, glaucoma can result in constricted visual field and eventually loss of central vision.

DBA/2J mice (8.5-month-old) were treated with either omega-3 (270 mg EPA and DHA) +timolol (0,5%) omega-3 only or timolol only, once daily for 3 months and there was also an untreated group. Treatment groups showed protection of retinal gagglion cells (RGCs), decreased blood AA/EPA ratio < 2 and reduced protein levels of inflammatory mediators TNF-a and IL-18

Quantification of Retinal Gagglion Cells density . Indicate a protective effect of Eyetas

RGC survival in the DBA/2J mice model after treatment with ω3-PUFAs + timolol, ω3-PUFAs, or timolol

Omega-3 fatty acids protect retinal neurons in the DBA/2J hereditary glaucoma mouse model Kalogerou et al, 2018

Supportive Research

The association between daily dietary intake of Omega 3 and the prevalence of glaucoma in the U.S. was examined in 3865 participants. The results showed that daily dietary intake of EPA and DHA was associated with lower likelihood of glaucomatous optic neuropathy.

Wang, et al. 2018

Patients with primary open angle glaucoma were compared with their healthy siblings and found that the glaucoma patients had reduced EPA and DHA fatty acids.

Ren, et al. 2006

Retinal ganglion cell survival is seen when Omega 3 is combined with eye drop treatment in hereditary glaucoma mouse models, which supports the neuroprotective effects of EPA and DHA when the correct dose is being given.

Kalogerou, et al. 2017

Glaucoma

Glaucoma

Supportive Research

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