Wet Age-Related Macular Degeneration​

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Wet Age-Related Macular Degeneration​

Age-related macular degeneration (AMD) is the leading cause of vision loss in people aged 50 or older. AMD does not lead to total blindness. It does however affect your central vision and interferes with your everyday tasks, such as reading and recognizing faces. Wet AMD is a less common form of AMD, caused by the growth of abnormal blood vessels at the back of the eyes and build-up of fluid under the retina. Current treatments with eye injections aim to help stop vision getting worse. Omega-3 has proven to better improve vision when combined with eye injections.

Eye injection combined with Omega 3 provide better visual outcome in wet AMD

Patients with Wet AMD were treated with eye injection with or without Omega 3.

Georgiou, et al. 2019

Supportive Research

Serum levels of eicosapentaenoic acid are associated with a significantly lower risk of choroidal neovascular AMD in a study of 290 patients with wet AMD and 144 controls without AMD. The red blood cell membrane levels of eicosapentaenoic and docosahexanoic fatty acids, which represent long-term levels of PUFAs, are associated strongly with a lower risk for choroidal neovascular AMD.

In a recent cross-sectional case-controlled study, neovascular AMD was associated with lower circulatory levels of Omega 3 and higher levels of Omega-6 fatty acids.

Omega-3 reduce choroidal neovascular AMD in a mouse model. The levels of VEGF and leukocytes infiltration were also reduced in the retina and choroid in the Omega 3 fed mouse model.

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